To get inside Dawn of Reason go around the side of the building and go through the opening above the door.
To open the gift in Dawn of Reason in Play Edward Scheme in Super Shifty in Karl’s Bay in Deathloop, you need to find the safe combination based on paintings on walls and furniture throughout the Dawn of Reason.
The outer ring indicates the number and the position of the red line in the middle of the ring indicates the order of the numbers. The paintings will appear in random locations throughout the Dawn of Reason, although one is always next to the locked door. Once you have found all the numbers, go down to the door, enter the code and open the gift inside.