After killing the monster, whatever it is called, the safe was standing on top of it with no obvious way of getting to it. I’m not sure if it is a bug or intentional, be sure to leave a comment below if the same happened to you. Here is a guide to explain how to get to the safe:
If you jump on the glowing legs of the monster:
You start bouncing around. Bounce towards the higher spikes of the glowing leg to gain height.
Eventually you get to the top, but you still bounce around. Try to get to the safe and open it by spamming the action key. If you fall of try again with the same method. The safe opens and you have to pick up 3 items out of it. Again, spam the action key until you get the pictures.
Eagle eyed people might spot the chest on another side of the monster:
For me there was only a bunch of ammunition in it, so it isn’t really worth the effort of getting to it since there is a vendor not far away.
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